Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Elagolix
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Elagolix: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak to moderate CYP3A4 inducer and may lower amlodipine levels. The effect is usually modest.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Elagolix belongs to Musculoskeletal.
Why it happens
CYP3A4 induction by elagolix increases amlodipine clearance.
What to do
Monitor blood pressure and adjust the amlodipine dose if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Elagolix?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak to moderate CYP3A4 inducer and may lower amlodipine levels. The effect is usually modest.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Elagolix?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and adjust the amlodipine dose if control worsens.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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