Drug interactions
Apomorphine + Indacaterol
Severity: Moderate
Apomorphine and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Apomorphine can prolong the QT interval and cause orthostatic hypotension and reflex tachycardia. Indacaterol may add to heart rate and QT effects. The combination may increase arrhythmia risk in susceptible patients.
What this interaction means in plain words
Apomorphine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Apomorphine belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation and cardiovascular stimulation.
What to do
Check baseline ECG and electrolytes in patients with QT risk factors, and monitor heart rate and blood pressure after dosing.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Apomorphine
- Alosetron + Apomorphine Contraindicated
- Apomorphine + Cisapride Contraindicated
- Apomorphine + Dolasetron Contraindicated
- Apomorphine + Granisetron Contraindicated
- Apomorphine + Netupitant-palonosetron Contraindicated
- Apomorphine + Ondansetron Contraindicated
Frequently asked questions
Can I take Apomorphine with Indacaterol?
MediHelp rates the interaction as moderate. Apomorphine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Apomorphine can prolong the QT interval and cause orthostatic hypotension and reflex tachycardia. Indacaterol may add to heart rate and QT effects. The combination may increase arrhythmia risk in susceptible patients.
How serious is the interaction between Apomorphine and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with QT risk factors, and monitor heart rate and blood pressure after dosing.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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