Drug interactions
Armodafinil + Ceritinib
Severity: Minor
Armodafinil and Ceritinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ceritinib inhibits CYP3A4 and may increase armodafinil concentrations, potentially increasing adverse effects such as anxiety, insomnia and headache.
What this interaction means in plain words
Armodafinil and Ceritinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Ceritinib belongs to Oncology.
Why it happens
Ceritinib inhibits CYP3A4, decreasing armodafinil metabolism.
What to do
Monitor for armodafinil adverse effects and reduce the dose if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Ceritinib
- Ceritinib + Cisapride Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Ceritinib + Pimozide Contraindicated
- Ceritinib + Thioridazine Contraindicated
- Ceritinib + Tolvaptan Contraindicated
Frequently asked questions
Can I take Armodafinil with Ceritinib?
MediHelp rates the interaction as minor. Armodafinil and Ceritinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ceritinib inhibits CYP3A4 and may increase armodafinil concentrations, potentially increasing adverse effects such as anxiety, insomnia and headache.
How serious is the interaction between Armodafinil and Ceritinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for armodafinil adverse effects and reduce the dose if they occur.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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