Drug interactions
Armodafinil + Eletriptan
Severity: Minor
Armodafinil and Eletriptan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eletriptan is cleared mainly by CYP3A4, and armodafinil is a weak inducer that may lower its levels. This may reduce migraine relief, though the effect is likely modest.
What this interaction means in plain words
Armodafinil and Eletriptan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Eletriptan belongs to Central Nervous System.
Why it happens
Armodafinil induces CYP3A4, increasing eletriptan metabolism.
What to do
Monitor migraine response and consider an alternative triptan if eletriptan seems less effective.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Eletriptan
- Almotriptan + Eletriptan Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Clarithromycin + Eletriptan Contraindicated
- Cobicistat + Eletriptan Contraindicated
- Conivaptan + Eletriptan Contraindicated
Frequently asked questions
Can I take Armodafinil with Eletriptan?
MediHelp rates the interaction as minor. Armodafinil and Eletriptan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eletriptan is cleared mainly by CYP3A4, and armodafinil is a weak inducer that may lower its levels. This may reduce migraine relief, though the effect is likely modest.
How serious is the interaction between Armodafinil and Eletriptan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor migraine response and consider an alternative triptan if eletriptan seems less effective.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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