Drug interactions
Armodafinil + Erythromycin lactobionate
Severity: Minor
Armodafinil and Erythromycin lactobionate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil may modestly lower erythromycin concentrations through CYP3A4 induction, possibly reducing antibacterial effect. The clinical impact is usually limited with intravenous dosing.
What this interaction means in plain words
Armodafinil and Erythromycin lactobionate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Erythromycin lactobionate belongs to Anti Bacterial.
Why it happens
Armodafinil induces CYP3A4, increasing the metabolism of erythromycin.
What to do
Monitor clinical response to the infection; consider an alternate antibiotic if treatment fails.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Erythromycin lactobionate
- Cisapride + Erythromycin lactobionate Contraindicated
- Dihydroergotamine + Erythromycin lactobionate Contraindicated
- Dronedarone + Erythromycin lactobionate Contraindicated
- Eletriptan + Erythromycin lactobionate Contraindicated
- Ergotamine + Erythromycin lactobionate Contraindicated
- Erythromycin lactobionate + Flibanserin Contraindicated
Frequently asked questions
Can I take Armodafinil with Erythromycin lactobionate?
MediHelp rates the interaction as minor. Armodafinil and Erythromycin lactobionate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil may modestly lower erythromycin concentrations through CYP3A4 induction, possibly reducing antibacterial effect. The clinical impact is usually limited with intravenous dosing.
How serious is the interaction between Armodafinil and Erythromycin lactobionate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to the infection; consider an alternate antibiotic if treatment fails.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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