Drug interactions
Armodafinil + Fenfluramine
Severity: Minor
Armodafinil and Fenfluramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenfluramine can cause insomnia and, in some patients, nervousness, while armodafinil is stimulating. Combined use may add to insomnia, agitation or raised blood pressure.
What this interaction means in plain words
Armodafinil and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Fenfluramine belongs to Central Nervous System.
Why it happens
Additive CNS stimulant pharmacodynamic effects.
What to do
Monitor sleep, mood, and blood pressure, and reduce the dose of one agent if stimulation becomes troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Fenfluramine
- Fenfluramine + Isocarboxazid Contraindicated
- Fenfluramine + Linezolid Contraindicated
- Fenfluramine + Phenelzine Contraindicated
- Fenfluramine + Selegiline Contraindicated
- Fenfluramine + Tranylcypromine Contraindicated
- Almotriptan + Fenfluramine Major
Frequently asked questions
Can I take Armodafinil with Fenfluramine?
MediHelp rates the interaction as minor. Armodafinil and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fenfluramine can cause insomnia and, in some patients, nervousness, while armodafinil is stimulating. Combined use may add to insomnia, agitation or raised blood pressure.
How serious is the interaction between Armodafinil and Fenfluramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sleep, mood, and blood pressure, and reduce the dose of one agent if stimulation becomes troublesome.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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