Drug interactions
Atazanavir + Ertugliflozin-sitagliptin
Severity: Minor
Atazanavir and Ertugliflozin-sitagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Protease inhibitors can cause insulin resistance and hyperglycemia, which may offset the glucose-lowering effect of antidiabetic therapy. Atazanavir is among the more metabolically neutral protease inhibitors, so the effect is typically modest.
What this interaction means in plain words
Atazanavir and Ertugliflozin-sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Ertugliflozin-sitagliptin belongs to Endocrine.
Why it happens
Protease inhibitor-associated insulin resistance and impaired glucose metabolism opposing antihyperglycemic action.
What to do
Monitor glucose and HbA1c after starting or changing the antiretroviral regimen, and adjust antidiabetic therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Ertugliflozin-sitagliptin?
MediHelp rates the interaction as minor. Atazanavir and Ertugliflozin-sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Protease inhibitors can cause insulin resistance and hyperglycemia, which may offset the glucose-lowering effect of antidiabetic therapy. Atazanavir is among the more metabolically neutral protease inhibitors, so the effect is typically modest.
How serious is the interaction between Atazanavir and Ertugliflozin-sitagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and HbA1c after starting or changing the antiretroviral regimen, and adjust antidiabetic therapy if control worsens.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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