Drug interactions
Bromocriptine + Lanreotide
Severity: Minor
Bromocriptine and Lanreotide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Somatostatin analogues can reduce the metabolic clearance of CYP450 substrates, so bromocriptine exposure might rise modestly. This could heighten bromocriptine adverse effects, although clinical significance is uncertain. The pair is sometimes used together deliberately in acromegaly.
What this interaction means in plain words
Bromocriptine and Lanreotide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bromocriptine belongs to Central Nervous System; Lanreotide belongs to Endocrine.
Why it happens
Suppression of growth hormone by somatostatin analogues may reduce CYP450-mediated clearance of bromocriptine; this is largely theoretical.
What to do
Monitor for bromocriptine adverse effects such as nausea and hypotension when starting lanreotide. Reduce the bromocriptine dose if these occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bromocriptine
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Bromocriptine with Lanreotide?
MediHelp rates the interaction as minor. Bromocriptine and Lanreotide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Somatostatin analogues can reduce the metabolic clearance of CYP450 substrates, so bromocriptine exposure might rise modestly. This could heighten bromocriptine adverse effects, although clinical significance is uncertain. The pair is sometimes used together deliberately in acromegaly.
How serious is the interaction between Bromocriptine and Lanreotide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bromocriptine adverse effects such as nausea and hypotension when starting lanreotide. Reduce the bromocriptine dose if these occur.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
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