Drug interactions
Bromocriptine + Lisdexamfetamine
Severity: Moderate
Bromocriptine and Lisdexamfetamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have dopaminergic and cardiovascular activity, and each can raise blood pressure. Together they may increase the risk of hypertension, tachyarrhythmia and psychiatric adverse effects such as agitation.
What this interaction means in plain words
Bromocriptine and Lisdexamfetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bromocriptine belongs to Central Nervous System; Lisdexamfetamine belongs to Central Nervous System.
Why it happens
Additive dopaminergic and sympathomimetic pharmacodynamic effects.
What to do
Monitor blood pressure, heart rate and mental status, especially after dose changes. Reduce the dose of one drug if hypertension or arrhythmia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lisdexamfetamine
- Isocarboxazid + Lisdexamfetamine Contraindicated
- Linezolid + Lisdexamfetamine Contraindicated
- Lisdexamfetamine + Phenelzine Contraindicated
- Lisdexamfetamine + Procarbazine Contraindicated
- Lisdexamfetamine + Rasagiline Contraindicated
- Lisdexamfetamine + Safinamide Contraindicated
Other interactions of Bromocriptine
Frequently asked questions
Can I take Bromocriptine with Lisdexamfetamine?
MediHelp rates the interaction as moderate. Bromocriptine and Lisdexamfetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have dopaminergic and cardiovascular activity, and each can raise blood pressure. Together they may increase the risk of hypertension, tachyarrhythmia and psychiatric adverse effects such as agitation.
How serious is the interaction between Bromocriptine and Lisdexamfetamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and mental status, especially after dose changes. Reduce the dose of one drug if hypertension or arrhythmia occurs.
What other medicines interact with Lisdexamfetamine?
MediHelp also lists interactions of Lisdexamfetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Lisdexamfetamine page.
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