Drug interactions
Cariprazine + Felbamate
Severity: Moderate
Cariprazine and Felbamate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause drowsiness and dizziness, so together they may increase sedation and impair alertness. Felbamate also affects other drug levels through enzyme effects, including weak CYP3A4 induction, which could modestly lower cariprazine exposure.
What this interaction means in plain words
Cariprazine and Felbamate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cariprazine belongs to Central Nervous System; Felbamate belongs to Central Nervous System.
Why it happens
Additive CNS depression; felbamate may also weakly induce CYP3A4.
What to do
Monitor for sedation and for changes in psychiatric response. Adjust cariprazine dose according to clinical effect.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cariprazine
Other interactions of Felbamate
- Felbamate + Ulipristal Major
- Amisulpride + Felbamate Moderate
- Amitriptyline + Felbamate Moderate
- Apalutamide + Felbamate Moderate
- Asenapine + Felbamate Moderate
- Bosentan + Felbamate Moderate
Frequently asked questions
Can I take Cariprazine with Felbamate?
MediHelp rates the interaction as moderate. Cariprazine and Felbamate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause drowsiness and dizziness, so together they may increase sedation and impair alertness. Felbamate also affects other drug levels through enzyme effects, including weak CYP3A4 induction, which could modestly lower cariprazine exposure.
How serious is the interaction between Cariprazine and Felbamate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and for changes in psychiatric response. Adjust cariprazine dose according to clinical effect.
What other medicines interact with Cariprazine?
MediHelp also lists interactions of Cariprazine with, for example, Alfentanil, Amisulpride, Amobarbital. The full list is on the Cariprazine page.
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