Drug interactions
Cefdinir + Cefpirome
Severity: Minor
Cefdinir and Cefpirome: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Two cephalosporins given together offer no therapeutic advantage, and both are renally secreted so concentrations could rise slightly. A meaningful clinical interaction is not documented.
What this interaction means in plain words
Cefdinir and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefdinir belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.
Why it happens
Theoretical competition for renal tubular secretion of anionic drugs.
What to do
Avoid duplicate cephalosporin therapy; if both are given, adjust doses for renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefdinir with Cefpirome?
MediHelp rates the interaction as minor. Cefdinir and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Two cephalosporins given together offer no therapeutic advantage, and both are renally secreted so concentrations could rise slightly. A meaningful clinical interaction is not documented.
How serious is the interaction between Cefdinir and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate cephalosporin therapy; if both are given, adjust doses for renal function.
What other medicines interact with Cefdinir?
MediHelp also lists interactions of Cefdinir with, for example, Aluminum hydroxide, Cholera vaccine, Famotidine. The full list is on the Cefdinir page.
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