Drug interactions
Cefditoren + Clarithromycin
Severity: Minor
Cefditoren and Clarithromycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bacteriostatic macrolides might theoretically reduce the bactericidal effect of beta-lactams. Combinations of a beta-lactam with a macrolide are widely used with no consistent evidence of reduced efficacy.
What this interaction means in plain words
Cefditoren and Clarithromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefditoren belongs to Anti Bacterial; Clarithromycin belongs to Anti Bacterial.
Why it happens
Theoretical pharmacodynamic antagonism, since beta-lactams need actively dividing bacteria and bacteriostatic drugs slow growth.
What to do
No routine change is needed when the combination is clinically indicated. Reassess clinical response if the infection is not improving.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Frequently asked questions
Can I take Cefditoren with Clarithromycin?
MediHelp rates the interaction as minor. Cefditoren and Clarithromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bacteriostatic macrolides might theoretically reduce the bactericidal effect of beta-lactams. Combinations of a beta-lactam with a macrolide are widely used with no consistent evidence of reduced efficacy.
How serious is the interaction between Cefditoren and Clarithromycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed when the combination is clinically indicated. Reassess clinical response if the infection is not improving.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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