Drug interactions
Cefpirome + Mycophenolate mofetil
Severity: Minor
Cefpirome and Mycophenolate mofetil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefpirome is renally eliminated and may compete with MPAG for tubular secretion. Clinical consequences are not well documented. Cephalosporins may also reduce mycophenolate exposure by altering gut flora.
What this interaction means in plain words
Cefpirome and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Mycophenolate mofetil belongs to Miscellaneous.
Why it happens
Possible competition for renal anionic secretion; antibiotics may reduce enterohepatic recirculation.
What to do
Monitor blood counts and clinical response; no routine dose adjustment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Mycophenolate mofetil?
MediHelp rates the interaction as minor. Cefpirome and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally eliminated and may compete with MPAG for tubular secretion. Clinical consequences are not well documented. Cephalosporins may also reduce mycophenolate exposure by altering gut flora.
How serious is the interaction between Cefpirome and Mycophenolate mofetil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and clinical response; no routine dose adjustment.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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