Drug interactions
Ceritinib + Indacaterol
Severity: Moderate
Ceritinib and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ceritinib prolongs the QT interval and can cause bradycardia. Indacaterol may add QT effects and tachycardia or hypokalemia. The combination may increase the risk of serious ventricular arrhythmia.
What this interaction means in plain words
Ceritinib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ceritinib belongs to Oncology; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG and electrolytes (potassium, magnesium) periodically, and reassess the combination if QTc becomes prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Ceritinib
- Ceritinib + Cisapride Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Ceritinib + Pimozide Contraindicated
- Ceritinib + Thioridazine Contraindicated
- Ceritinib + Tolvaptan Contraindicated
Frequently asked questions
Can I take Ceritinib with Indacaterol?
MediHelp rates the interaction as moderate. Ceritinib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ceritinib prolongs the QT interval and can cause bradycardia. Indacaterol may add QT effects and tachycardia or hypokalemia. The combination may increase the risk of serious ventricular arrhythmia.
How serious is the interaction between Ceritinib and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes (potassium, magnesium) periodically, and reassess the combination if QTc becomes prolonged.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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