Drug interactions
Chloroquine + Indacaterol
Severity: Moderate
Chloroquine and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine prolongs the QT interval and can provoke ventricular arrhythmias, and indacaterol may add to this through tachycardia and lowered potassium. The risk is greater with cardiac disease, electrolyte imbalance or other QT-prolonging drugs.
What this interaction means in plain words
Chloroquine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation and beta2-agonist-related hypokalemia and sympathetic stimulation.
What to do
Check ECG and correct potassium and magnesium before and during combined use. Consider an alternative bronchodilator or antimalarial if the QT interval is already prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Indacaterol?
MediHelp rates the interaction as moderate. Chloroquine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine prolongs the QT interval and can provoke ventricular arrhythmias, and indacaterol may add to this through tachycardia and lowered potassium. The risk is greater with cardiac disease, electrolyte imbalance or other QT-prolonging drugs.
How serious is the interaction between Chloroquine and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and correct potassium and magnesium before and during combined use. Consider an alternative bronchodilator or antimalarial if the QT interval is already prolonged.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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