Drug interactions
Chlorpheniramine + Hawthorn
Severity: Minor
Chlorpheniramine and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has been reported to have mild sedative properties, so it could add to the drowsiness caused by chlorpheniramine. The supporting evidence is limited and the effect is probably modest.
What this interaction means in plain words
Chlorpheniramine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlorpheniramine belongs to Respiratory; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive sedation; the mechanism is not well established.
What to do
Advise the patient to watch for increased drowsiness and avoid driving if affected. No dose change is normally needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chlorpheniramine and Hawthorn, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Chlorpheniramine
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Chlorpheniramine with Hawthorn?
MediHelp rates the interaction as minor. Chlorpheniramine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has been reported to have mild sedative properties, so it could add to the drowsiness caused by chlorpheniramine. The supporting evidence is limited and the effect is probably modest.
How serious is the interaction between Chlorpheniramine and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient to watch for increased drowsiness and avoid driving if affected. No dose change is normally needed.
What other medicines interact with Chlorpheniramine?
MediHelp also lists interactions of Chlorpheniramine with, for example, Belladonna and opium, Benzhydrocodone / acetaminophen, Brexanolone. The full list is on the Chlorpheniramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
