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Drug interactions

Cilostazol + Porfimer

Severity: Moderate

Cilostazol and Porfimer: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Porfimer photodynamic therapy relies on light-activated photochemical damage and thrombosis of tumor vessels. Antiplatelet drugs such as cilostazol might reduce this effect, although clinical data are limited.

What this interaction means in plain words

Cilostazol and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cilostazol belongs to Cardiovascular; Porfimer belongs to Miscellaneous.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic antagonism: platelet inhibition may blunt thrombus formation contributing to porfimer's photodynamic effect.

What to do

Consider whether cilostazol can be held around photodynamic therapy, weighing vascular needs. Monitor treatment response.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cilostazol with Porfimer?

MediHelp rates the interaction as moderate. Cilostazol and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer photodynamic therapy relies on light-activated photochemical damage and thrombosis of tumor vessels. Antiplatelet drugs such as cilostazol might reduce this effect, although clinical data are limited.

How serious is the interaction between Cilostazol and Porfimer?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider whether cilostazol can be held around photodynamic therapy, weighing vascular needs. Monitor treatment response.

What other medicines interact with Cilostazol?

MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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