Drug interactions
Cimetidine + Felbamate
Severity: Minor
Cimetidine and Felbamate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Felbamate inhibits CYP2C19 and might modestly raise cimetidine levels. This is unlikely to be clinically important.
What this interaction means in plain words
Cimetidine and Felbamate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cimetidine belongs to Gastrointestinal Tract; Felbamate belongs to Central Nervous System.
Why it happens
Felbamate inhibits CYP2C19, which contributes to cimetidine metabolism.
What to do
No routine action is needed; monitor for cimetidine adverse effects such as confusion in vulnerable patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Other interactions of Felbamate
- Felbamate + Ulipristal Major
- Amisulpride + Felbamate Moderate
- Amitriptyline + Felbamate Moderate
- Apalutamide + Felbamate Moderate
- Asenapine + Felbamate Moderate
- Bosentan + Felbamate Moderate
Frequently asked questions
Can I take Cimetidine with Felbamate?
MediHelp rates the interaction as minor. Cimetidine and Felbamate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Felbamate inhibits CYP2C19 and might modestly raise cimetidine levels. This is unlikely to be clinically important.
How serious is the interaction between Cimetidine and Felbamate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor for cimetidine adverse effects such as confusion in vulnerable patients.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
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