Drug interactions
Dasatinib + Maraviroc
Severity: Minor
Dasatinib and Maraviroc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib may weakly inhibit CYP3A4 and slightly raise maraviroc exposure. Clinically significant effects are unlikely, though maraviroc can cause postural hypotension and hepatotoxicity.
What this interaction means in plain words
Dasatinib and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasatinib belongs to Oncology; Maraviroc belongs to Anti Virals.
Why it happens
Weak CYP3A4 inhibition reducing maraviroc metabolism.
What to do
No dose change is usually needed; monitor for dizziness and liver function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Dasatinib with Maraviroc?
MediHelp rates the interaction as minor. Dasatinib and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib may weakly inhibit CYP3A4 and slightly raise maraviroc exposure. Clinically significant effects are unlikely, though maraviroc can cause postural hypotension and hepatotoxicity.
How serious is the interaction between Dasatinib and Maraviroc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for dizziness and liver function.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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