Drug interactions
Digoxin + Miglitol
Severity: Minor
Digoxin and Miglitol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Miglitol has been reported to lower digoxin concentrations in some data, but the effect is inconsistent and of uncertain clinical importance.
What this interaction means in plain words
Digoxin and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Digoxin belongs to Cardiovascular; Miglitol belongs to Endocrine.
Why it happens
Mechanism not established; possible reduced digoxin absorption.
What to do
Check digoxin levels or clinical response if miglitol is started or stopped in a patient on digoxin. Adjust the digoxin dose if levels fall.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Digoxin
- Digoxin + Lily of the valley Contraindicated
- Digoxin + Squill Contraindicated
- Adagrasib + Digoxin Major
- Amiodarone + Digoxin Major
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Major
- Amphotericin b deoxycholate + Digoxin Major
Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Frequently asked questions
Can I take Digoxin with Miglitol?
MediHelp rates the interaction as minor. Digoxin and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Miglitol has been reported to lower digoxin concentrations in some data, but the effect is inconsistent and of uncertain clinical importance.
How serious is the interaction between Digoxin and Miglitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check digoxin levels or clinical response if miglitol is started or stopped in a patient on digoxin. Adjust the digoxin dose if levels fall.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
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