Drug interactions
Dolasetron + Triclabendazole
Severity: Moderate
Dolasetron and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval. Triclabendazole labeling describes QT prolongation, so combined use may increase the risk of torsades de pointes. Risk is higher with bradycardia, electrolyte abnormalities or congenital long QT.
What this interaction means in plain words
Dolasetron and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dolasetron belongs to Gastrointestinal Tract; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive delayed ventricular repolarization.
What to do
Obtain a baseline ECG and correct hypokalemia and hypomagnesemia. Prefer a non-QT-prolonging antiemetic where possible, and monitor the ECG if the combination is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dolasetron
- Apomorphine + Dolasetron Contraindicated
- Dofetilide + Dolasetron Contraindicated
- Dolasetron + Ibutilide Contraindicated
- Dolasetron + Pimozide Contraindicated
- Dolasetron + Thioridazine Contraindicated
- Dolasetron + Vandetanib Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Dolasetron with Triclabendazole?
MediHelp rates the interaction as moderate. Dolasetron and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval. Triclabendazole labeling describes QT prolongation, so combined use may increase the risk of torsades de pointes. Risk is higher with bradycardia, electrolyte abnormalities or congenital long QT.
How serious is the interaction between Dolasetron and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct hypokalemia and hypomagnesemia. Prefer a non-QT-prolonging antiemetic where possible, and monitor the ECG if the combination is needed.
What other medicines interact with Dolasetron?
MediHelp also lists interactions of Dolasetron with, for example, Apomorphine, Dofetilide, Ibutilide. The full list is on the Dolasetron page.
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