Drug interactions
Eletriptan + Rucaparib
Severity: Minor
Eletriptan and Rucaparib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rucaparib is a weak-to-moderate CYP3A4 inhibitor and may modestly raise eletriptan levels. Clinically relevant effects are probably limited.
What this interaction means in plain words
Eletriptan and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eletriptan belongs to Central Nervous System; Rucaparib belongs to Oncology.
Why it happens
Rucaparib inhibits CYP3A4, reducing eletriptan metabolism.
What to do
Monitor for increased triptan adverse effects such as blood pressure elevation and chest tightness, and lower the eletriptan dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eletriptan
- Almotriptan + Eletriptan Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Clarithromycin + Eletriptan Contraindicated
- Cobicistat + Eletriptan Contraindicated
- Conivaptan + Eletriptan Contraindicated
Other interactions of Rucaparib
- Cisapride + Rucaparib Major
- Ergotamine + Rucaparib Major
- Pimozide + Rucaparib Major
- Alfuzosin + Rucaparib Moderate
- Aripiprazole + Rucaparib Moderate
- Atorvastatin + Rucaparib Moderate
Frequently asked questions
Can I take Eletriptan with Rucaparib?
MediHelp rates the interaction as minor. Eletriptan and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rucaparib is a weak-to-moderate CYP3A4 inhibitor and may modestly raise eletriptan levels. Clinically relevant effects are probably limited.
How serious is the interaction between Eletriptan and Rucaparib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased triptan adverse effects such as blood pressure elevation and chest tightness, and lower the eletriptan dose if needed.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
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