Drug interactions
Enzalutamide + Ritlecitinib
Severity: Moderate
Enzalutamide and Ritlecitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Strong CYP3A inducers can reduce ritlecitinib exposure. Enzalutamide may therefore cause loss of efficacy in alopecia areata.
What this interaction means in plain words
Enzalutamide and Ritlecitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enzalutamide belongs to Endocrine; Ritlecitinib belongs to Oncology.
Why it happens
Enzalutamide induces CYP3A4 and other enzymes, increasing ritlecitinib clearance.
What to do
Avoid the combination if possible; if used, monitor for reduced therapeutic response to ritlecitinib.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enzalutamide
- Doravirine + Enzalutamide Contraindicated
- Elbasvir / grazoprevir + Enzalutamide Contraindicated
- Ensitrelvir + Enzalutamide Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Enzalutamide + Isavuconazonium Contraindicated
- Enzalutamide + Lenacapavir Contraindicated
Other interactions of Ritlecitinib
Frequently asked questions
Can I take Enzalutamide with Ritlecitinib?
MediHelp rates the interaction as moderate. Enzalutamide and Ritlecitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Strong CYP3A inducers can reduce ritlecitinib exposure. Enzalutamide may therefore cause loss of efficacy in alopecia areata.
How serious is the interaction between Enzalutamide and Ritlecitinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible; if used, monitor for reduced therapeutic response to ritlecitinib.
What other medicines interact with Enzalutamide?
MediHelp also lists interactions of Enzalutamide with, for example, Doravirine, Elbasvir / grazoprevir, Ensitrelvir. The full list is on the Enzalutamide page.
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