Drug interactions
Ergotamine + Finerenone
Severity: Minor
Ergotamine and Finerenone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ergotamine is a CYP3A4 substrate with limited inhibitory activity, so a clinically meaningful rise in finerenone exposure is uncertain. Any increase could raise the risk of hyperkalemia and hypotension.
What this interaction means in plain words
Ergotamine and Finerenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ergotamine belongs to Central Nervous System; Finerenone belongs to Cardiovascular.
Why it happens
Possible weak CYP3A4 inhibition by ergotamine reducing finerenone clearance.
What to do
Check serum potassium and renal function when starting or changing doses of either drug. Adjust the finerenone dose if potassium rises.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ergotamine
- Almotriptan + Ergotamine Contraindicated
- Atazanavir + Ergotamine Contraindicated
- Clarithromycin + Ergotamine Contraindicated
- Cobicistat + Ergotamine Contraindicated
- Darunavir + Ergotamine Contraindicated
- Dihydroergotamine intranasal + Ergotamine Contraindicated
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Ergotamine with Finerenone?
MediHelp rates the interaction as minor. Ergotamine and Finerenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ergotamine is a CYP3A4 substrate with limited inhibitory activity, so a clinically meaningful rise in finerenone exposure is uncertain. Any increase could raise the risk of hyperkalemia and hypotension.
How serious is the interaction between Ergotamine and Finerenone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and renal function when starting or changing doses of either drug. Adjust the finerenone dose if potassium rises.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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