Drug interactions
Ertugliflozin-sitagliptin + Ritonavir
Severity: Moderate
Ertugliflozin-sitagliptin and Ritonavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ritonavir can cause insulin resistance and hyperglycemia, which may reduce antidiabetic efficacy. Glycemic control may worsen.
What this interaction means in plain words
Ertugliflozin-sitagliptin and Ritonavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ertugliflozin-sitagliptin belongs to Endocrine; Ritonavir belongs to Anti Virals.
Why it happens
Protease inhibitor associated insulin resistance and altered glucose metabolism.
What to do
Monitor blood glucose when ritonavir is started or stopped and adjust antidiabetic therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Ritonavir
- Alfuzosin + Ritonavir Contraindicated
- Amiodarone + Ritonavir Contraindicated
- Avanafil + Ritonavir Contraindicated
- Colchicine + Ritonavir Contraindicated
- Dronedarone + Ritonavir Contraindicated
- Eletriptan + Ritonavir Contraindicated
Frequently asked questions
Can I take Ertugliflozin-sitagliptin with Ritonavir?
MediHelp rates the interaction as moderate. Ertugliflozin-sitagliptin and Ritonavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ritonavir can cause insulin resistance and hyperglycemia, which may reduce antidiabetic efficacy. Glycemic control may worsen.
How serious is the interaction between Ertugliflozin-sitagliptin and Ritonavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when ritonavir is started or stopped and adjust antidiabetic therapy.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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