Drug interactions
Eslicarbazepine + Maraviroc
Severity: Major
Eslicarbazepine and Maraviroc: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine may reduce maraviroc exposure, risking loss of antiviral efficacy. Maraviroc labeling calls for dose adjustment with CYP3A4 inducers.
What this interaction means in plain words
Eslicarbazepine and Maraviroc can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Eslicarbazepine belongs to Central Nervous System; Maraviroc belongs to Anti Virals.
Why it happens
CYP3A4 induction by eslicarbazepine increases maraviroc metabolism.
What to do
Adjust the maraviroc dose according to labeling for inducers, taking into account any concomitant CYP3A4 inhibitor, and monitor viral load.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Eslicarbazepine with Maraviroc?
MediHelp rates the interaction as major. Eslicarbazepine and Maraviroc can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eslicarbazepine may reduce maraviroc exposure, risking loss of antiviral efficacy. Maraviroc labeling calls for dose adjustment with CYP3A4 inducers.
How serious is the interaction between Eslicarbazepine and Maraviroc?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Adjust the maraviroc dose according to labeling for inducers, taking into account any concomitant CYP3A4 inhibitor, and monitor viral load.
What other medicines interact with Eslicarbazepine?
MediHelp also lists interactions of Eslicarbazepine with, for example, Mavacamten, Rilpivirine, Artemether / lumefantrine. The full list is on the Eslicarbazepine page.
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