Drug interactions
Esomeprazole + Ferric maltol
Severity: Minor
Esomeprazole and Ferric maltol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reduced gastric acid may lower absorption of oral iron. Ferric maltol is less acid-dependent than ferrous salts, but PPIs may still reduce iron uptake somewhat.
What this interaction means in plain words
Esomeprazole and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Esomeprazole belongs to Gastrointestinal Tract; Ferric maltol belongs to Miscellaneous.
Why it happens
Higher gastric pH reduces iron solubility and absorption.
What to do
Monitor hemoglobin and ferritin; ferric maltol labeling does not require dose change, but consider alternative iron routes if response is poor.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esomeprazole
- Esomeprazole + Mavacamten Contraindicated
- Esomeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Esomeprazole Major
- Atazanavir + Esomeprazole Major
- Citalopram + Esomeprazole Major
- Clopidogrel + Esomeprazole Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Esomeprazole with Ferric maltol?
MediHelp rates the interaction as minor. Esomeprazole and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced gastric acid may lower absorption of oral iron. Ferric maltol is less acid-dependent than ferrous salts, but PPIs may still reduce iron uptake somewhat.
How serious is the interaction between Esomeprazole and Ferric maltol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin; ferric maltol labeling does not require dose change, but consider alternative iron routes if response is poor.
What other medicines interact with Esomeprazole?
MediHelp also lists interactions of Esomeprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Esomeprazole page.
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