Drug interactions
Estradiol + Ferric maltol
Severity: Minor
Estradiol and Ferric maltol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron products may bind with some co-administered oral drugs in the gut and lower their absorption. Estradiol exposure could therefore fall, potentially reducing hormonal effect. The label advises separating ferric maltol from susceptible oral drugs.
What this interaction means in plain words
Estradiol and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Estradiol belongs to Endocrine; Ferric maltol belongs to Miscellaneous.
Why it happens
Iron may chelate or form complexes with some oral drugs in the gastrointestinal tract, reducing absorption.
What to do
Separate estradiol and ferric maltol by at least 4 hours. Monitor for loss of estrogenic effect or breakthrough bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Other interactions of Estradiol
- Anastrozole + Estradiol Contraindicated
- Estradiol + Fezolinetant Contraindicated
- Estradiol + Ospemifene Contraindicated
- Antithrombin alfa + Estradiol Major
- Antithrombin iii + Estradiol Major
- Estradiol + Exemestane Major
Frequently asked questions
Can I take Estradiol with Ferric maltol?
MediHelp rates the interaction as minor. Estradiol and Ferric maltol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral iron products may bind with some co-administered oral drugs in the gut and lower their absorption. Estradiol exposure could therefore fall, potentially reducing hormonal effect. The label advises separating ferric maltol from susceptible oral drugs.
How serious is the interaction between Estradiol and Ferric maltol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate estradiol and ferric maltol by at least 4 hours. Monitor for loss of estrogenic effect or breakthrough bleeding.
What other medicines interact with Ferric maltol?
MediHelp also lists interactions of Ferric maltol with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Ferric maltol page.
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