Drug interactions
Everolimus + Omaveloxolone
Severity: Minor
Everolimus and Omaveloxolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omaveloxolone may induce CYP3A4 and slightly lower everolimus exposure. This could reduce everolimus efficacy.
What this interaction means in plain words
Everolimus and Omaveloxolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Everolimus belongs to Oncology; Omaveloxolone belongs to Central Nervous System.
Why it happens
Omaveloxolone induces CYP3A4, increasing everolimus metabolism.
What to do
Monitor everolimus trough levels and clinical response, and increase the everolimus dose if concentrations fall below target.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Omaveloxolone
Frequently asked questions
Can I take Everolimus with Omaveloxolone?
MediHelp rates the interaction as minor. Everolimus and Omaveloxolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omaveloxolone may induce CYP3A4 and slightly lower everolimus exposure. This could reduce everolimus efficacy.
How serious is the interaction between Everolimus and Omaveloxolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor everolimus trough levels and clinical response, and increase the everolimus dose if concentrations fall below target.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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