Drug interactions
Fenofibric acid + Furosemide
Severity: Minor
Fenofibric acid and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are highly protein bound and may compete for albumin binding, potentially raising free concentrations of either, particularly in hypoalbuminemia. Clinically significant effects are uncommon.
What this interaction means in plain words
Fenofibric acid and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenofibric acid belongs to Cardiovascular; Furosemide belongs to Cardiovascular.
Why it happens
Possible competition for plasma protein binding sites, increasing the free fraction of each drug.
What to do
Monitor for enhanced diuretic effect and fibrate adverse effects in patients with low albumin. Adjust doses based on response and renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Frequently asked questions
Can I take Fenofibric acid with Furosemide?
MediHelp rates the interaction as minor. Fenofibric acid and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are highly protein bound and may compete for albumin binding, potentially raising free concentrations of either, particularly in hypoalbuminemia. Clinically significant effects are uncommon.
How serious is the interaction between Fenofibric acid and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for enhanced diuretic effect and fibrate adverse effects in patients with low albumin. Adjust doses based on response and renal function.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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