Drug interactions
Fenofibric acid + Rosuvastatin
Severity: Moderate
Fenofibric acid and Rosuvastatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenofibric acid with rosuvastatin may modestly increase the risk of muscle toxicity. Risk is higher in renal impairment and the elderly.
What this interaction means in plain words
Fenofibric acid and Rosuvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fenofibric acid belongs to Cardiovascular; Rosuvastatin belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic myotoxicity.
What to do
Use the lowest effective doses and monitor renal function. Check CK in patients with muscle symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Rosuvastatin
Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Frequently asked questions
Can I take Fenofibric acid with Rosuvastatin?
MediHelp rates the interaction as moderate. Fenofibric acid and Rosuvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenofibric acid with rosuvastatin may modestly increase the risk of muscle toxicity. Risk is higher in renal impairment and the elderly.
How serious is the interaction between Fenofibric acid and Rosuvastatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor renal function. Check CK in patients with muscle symptoms.
What other medicines interact with Rosuvastatin?
MediHelp also lists interactions of Rosuvastatin with, for example, Atazanavir, Cyclosporine, Cyclosporin. The full list is on the Rosuvastatin page.
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