Drug interactions
Flecainide + Hawthorn
Severity: Minor
Flecainide and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties including positive inotropic and vasodilating effects and may modify the response to antiarrhythmic drugs. Any interaction with flecainide is poorly characterized and mainly theoretical.
What this interaction means in plain words
Flecainide and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flecainide belongs to Cardiovascular; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive pharmacodynamic cardiac effects; no established pharmacokinetic mechanism.
What to do
Ask patients about herbal use and advise against starting hawthorn without review. Monitor heart rate, blood pressure and ECG if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flecainide
- Flecainide + Nirmatrelvir Contraindicated
- Flecainide + Nirmatrelvir / ritonavir Contraindicated
- Flecainide + Pimozide Contraindicated
- Flecainide + Ritonavir Contraindicated
- Flecainide + Thioridazine Contraindicated
- Flecainide + Tipranavir Contraindicated
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Flecainide with Hawthorn?
MediHelp rates the interaction as minor. Flecainide and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has cardioactive properties including positive inotropic and vasodilating effects and may modify the response to antiarrhythmic drugs. Any interaction with flecainide is poorly characterized and mainly theoretical.
How serious is the interaction between Flecainide and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise against starting hawthorn without review. Monitor heart rate, blood pressure and ECG if it is used.
What other medicines interact with Flecainide?
MediHelp also lists interactions of Flecainide with, for example, Nirmatrelvir, Nirmatrelvir / ritonavir, Pimozide. The full list is on the Flecainide page.
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