Drug interactions
Fluphenazine + Maraviroc
Severity: Minor
Fluphenazine and Maraviroc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc is described as a weak CYP2D6 inhibitor in vitro, which could slightly raise fluphenazine levels. Clinical effect is not established.
What this interaction means in plain words
Fluphenazine and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluphenazine belongs to Central Nervous System; Maraviroc belongs to Anti Virals.
Why it happens
Possible weak inhibition of CYP2D6-mediated fluphenazine metabolism.
What to do
No dose change is usually needed; monitor for extrapyramidal symptoms and sedation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluphenazine
- Arsenic trioxide + Fluphenazine Contraindicated
- Dofetilide + Fluphenazine Contraindicated
- Fluphenazine + Ibutilide Contraindicated
- Fluphenazine + Pimozide Contraindicated
- Adagrasib + Fluphenazine Major
- Alfentanil + Fluphenazine Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Fluphenazine with Maraviroc?
MediHelp rates the interaction as minor. Fluphenazine and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc is described as a weak CYP2D6 inhibitor in vitro, which could slightly raise fluphenazine levels. Clinical effect is not established.
How serious is the interaction between Fluphenazine and Maraviroc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for extrapyramidal symptoms and sedation.
What other medicines interact with Fluphenazine?
MediHelp also lists interactions of Fluphenazine with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Fluphenazine page.
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