Drug interactions
Gemifloxacin + Sodium zirconium cyclosilicate
Severity: Minor
Gemifloxacin and Sodium zirconium cyclosilicate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sodium zirconium cyclosilicate can transiently raise gastric pH, which may alter the absorption of drugs whose solubility depends on acidity. The effect on gemifloxacin is theoretical and likely small, but it could reduce antibiotic exposure.
What this interaction means in plain words
Gemifloxacin and Sodium zirconium cyclosilicate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gemifloxacin belongs to Anti Bacterial; Sodium zirconium cyclosilicate belongs to Miscellaneous.
Why it happens
Possible reduction in oral absorption due to an increase in gastric pH.
What to do
Give gemifloxacin at least 2 hours before or after sodium zirconium cyclosilicate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Other interactions of Sodium zirconium cyclosilicate
- Cefditoren + Sodium zirconium cyclosilicate Moderate
- Cefpodoxime + Sodium zirconium cyclosilicate Moderate
- Cefuroxime + Sodium zirconium cyclosilicate Moderate
- Crizotinib + Sodium zirconium cyclosilicate Moderate
- Dasatinib + Sodium zirconium cyclosilicate Moderate
- Erlotinib + Sodium zirconium cyclosilicate Moderate
Frequently asked questions
Can I take Gemifloxacin with Sodium zirconium cyclosilicate?
MediHelp rates the interaction as minor. Gemifloxacin and Sodium zirconium cyclosilicate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sodium zirconium cyclosilicate can transiently raise gastric pH, which may alter the absorption of drugs whose solubility depends on acidity. The effect on gemifloxacin is theoretical and likely small, but it could reduce antibiotic exposure.
How serious is the interaction between Gemifloxacin and Sodium zirconium cyclosilicate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gemifloxacin at least 2 hours before or after sodium zirconium cyclosilicate.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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