Drug interactions
Glucagon + Tiotropium-olodaterol
Severity: Minor
Glucagon and Tiotropium-olodaterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon inhibits gastrointestinal motility, and the anticholinergic tiotropium may add to this effect. In practice the interaction is mainly relevant to diagnostic GI use of glucagon, and systemic absorption of inhaled tiotropium is low.
What this interaction means in plain words
Glucagon and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glucagon belongs to Endocrine; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
Additive suppression of gastrointestinal motility from glucagon and anticholinergic activity.
What to do
No dose change is usually needed. Monitor for constipation, abdominal distension or urinary retention in susceptible patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tiotropium-olodaterol
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
Frequently asked questions
Can I take Glucagon with Tiotropium-olodaterol?
MediHelp rates the interaction as minor. Glucagon and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon inhibits gastrointestinal motility, and the anticholinergic tiotropium may add to this effect. In practice the interaction is mainly relevant to diagnostic GI use of glucagon, and systemic absorption of inhaled tiotropium is low.
How serious is the interaction between Glucagon and Tiotropium-olodaterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed. Monitor for constipation, abdominal distension or urinary retention in susceptible patients.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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