Drug interactions
Hawthorn + Propafenone
Severity: Minor
Hawthorn and Propafenone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties, including positive inotropic, vasodilating and possible antiarrhythmic effects. It could add to the cardiac effects of propafenone, but clinical data are limited and the interaction is largely theoretical.
What this interaction means in plain words
Hawthorn and Propafenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hawthorn belongs to Gastrointestinal Tract; Propafenone belongs to Cardiovascular.
Why it happens
Possible additive pharmacodynamic cardiac effects; not well established.
What to do
Advise patients to tell their clinician about hawthorn use, and monitor heart rate, blood pressure and ECG if it is continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propafenone
- Dofetilide + Propafenone Contraindicated
- Dronedarone + Propafenone Contraindicated
- Nilotinib + Propafenone Contraindicated
- Nirmatrelvir / ritonavir + Propafenone Contraindicated
- Nirmatrelvir + Propafenone Contraindicated
- Pimozide + Propafenone Contraindicated
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Propafenone?
MediHelp rates the interaction as minor. Hawthorn and Propafenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has cardioactive properties, including positive inotropic, vasodilating and possible antiarrhythmic effects. It could add to the cardiac effects of propafenone, but clinical data are limited and the interaction is largely theoretical.
How serious is the interaction between Hawthorn and Propafenone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to tell their clinician about hawthorn use, and monitor heart rate, blood pressure and ECG if it is continued.
What other medicines interact with Propafenone?
MediHelp also lists interactions of Propafenone with, for example, Dofetilide, Dronedarone, Nilotinib. The full list is on the Propafenone page.
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