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Drug interactions

Hawthorn + Quetiapine

Severity: Minor

Hawthorn and Quetiapine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Evidence for a QT interaction with hawthorn is weak, and hawthorn is not an established QT-prolonging agent. Hawthorn has cardiovascular activity, so additive hypotension with quetiapine is conceivable but poorly documented.

What this interaction means in plain words

Hawthorn and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Hawthorn belongs to Gastrointestinal Tract; Quetiapine belongs to Central Nervous System.

Evidence level: Low

Why it happens

Not well established; possible additive hypotensive or cardiac effects.

What to do

Ask patients about herbal use and monitor blood pressure and heart rhythm if the combination is used. Obtain an ECG in patients who have other QT risk factors.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Hawthorn with Quetiapine?

MediHelp rates the interaction as minor. Hawthorn and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Evidence for a QT interaction with hawthorn is weak, and hawthorn is not an established QT-prolonging agent. Hawthorn has cardiovascular activity, so additive hypotension with quetiapine is conceivable but poorly documented.

How serious is the interaction between Hawthorn and Quetiapine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and monitor blood pressure and heart rhythm if the combination is used. Obtain an ECG in patients who have other QT risk factors.

What other medicines interact with Quetiapine?

MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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