Drug interactions
Hawthorn + Quinidine
Severity: Moderate
Hawthorn and Quinidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive effects, including positive inotropy, vasodilation and possible effects on cardiac conduction. Taken with quinidine it could add to hypotension or rhythm effects. Clinical evidence is limited.
What this interaction means in plain words
Hawthorn and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hawthorn belongs to Gastrointestinal Tract; Quinidine belongs to Anti Parasitic.
Why it happens
Additive pharmacodynamic cardiovascular effects are proposed, but the mechanism is not well established.
What to do
Ask patients on quinidine to avoid hawthorn products unless a prescriber has approved them. If both are used, monitor blood pressure, heart rate and the ECG.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Quinidine?
MediHelp rates the interaction as moderate. Hawthorn and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has cardioactive effects, including positive inotropy, vasodilation and possible effects on cardiac conduction. Taken with quinidine it could add to hypotension or rhythm effects. Clinical evidence is limited.
How serious is the interaction between Hawthorn and Quinidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients on quinidine to avoid hawthorn products unless a prescriber has approved them. If both are used, monitor blood pressure, heart rate and the ECG.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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