Drug interactions
Hawthorn + Verapamil
Severity: Moderate
Hawthorn and Verapamil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has vasodilating and mild negative chronotropic effects that may add to those of verapamil. This could cause hypotension or bradycardia. Clinical evidence is limited.
What this interaction means in plain words
Hawthorn and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hawthorn belongs to Gastrointestinal Tract; Verapamil belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic effects on blood pressure and cardiac conduction; hawthorn may have calcium channel blocking properties.
What to do
Monitor blood pressure and heart rate if the patient uses hawthorn. Advise the patient to discuss herbal use before starting.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Verapamil?
MediHelp rates the interaction as moderate. Hawthorn and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hawthorn has vasodilating and mild negative chronotropic effects that may add to those of verapamil. This could cause hypotension or bradycardia. Clinical evidence is limited.
How serious is the interaction between Hawthorn and Verapamil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate if the patient uses hawthorn. Advise the patient to discuss herbal use before starting.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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