Drug interactions
Human papillomavirus vaccine + Rilonacept
Severity: Minor
Human papillomavirus vaccine and Rilonacept: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rilonacept blocks interleukin-1 signaling and may theoretically affect immune responses, but a clinically important reduction in inactivated vaccine response is not established.
What this interaction means in plain words
Human papillomavirus vaccine and Rilonacept have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Human papillomavirus vaccine belongs to Miscellaneous; Rilonacept belongs to Miscellaneous.
Why it happens
IL-1 blockade may theoretically dampen vaccine immune responses; not firmly established.
What to do
Non-live HPV vaccine may be given during rilonacept therapy. Complete the series before starting treatment when convenient.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Rilonacept
Frequently asked questions
Can I take Human papillomavirus vaccine with Rilonacept?
MediHelp rates the interaction as minor. Human papillomavirus vaccine and Rilonacept have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rilonacept blocks interleukin-1 signaling and may theoretically affect immune responses, but a clinically important reduction in inactivated vaccine response is not established.
How serious is the interaction between Human papillomavirus vaccine and Rilonacept?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Non-live HPV vaccine may be given during rilonacept therapy. Complete the series before starting treatment when convenient.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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