Drug interactions
Hydrochlorothiazide + Mometasone
Severity: Minor
Hydrochlorothiazide and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both corticosteroids and thiazide diuretics can lower serum potassium. With inhaled mometasone the systemic exposure is low, so the effect is usually minimal.
What this interaction means in plain words
Hydrochlorothiazide and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide belongs to Cardiovascular; Mometasone belongs to Respiratory.
Why it happens
Additive renal potassium loss; limited by low systemic exposure of inhaled mometasone.
What to do
Check potassium periodically if other risk factors are present. No routine action is needed otherwise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Other interactions of Hydrochlorothiazide
Frequently asked questions
Can I take Hydrochlorothiazide with Mometasone?
MediHelp rates the interaction as minor. Hydrochlorothiazide and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both corticosteroids and thiazide diuretics can lower serum potassium. With inhaled mometasone the systemic exposure is low, so the effect is usually minimal.
How serious is the interaction between Hydrochlorothiazide and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium periodically if other risk factors are present. No routine action is needed otherwise.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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