Drug interactions
Hydrochlorothiazide-lisinopril + Verteporfin
Severity: Minor
Hydrochlorothiazide-lisinopril and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics are photosensitizing, and verteporfin is a photosensitizer used in photodynamic therapy. Combining them may increase the risk of skin photosensitivity reactions after treatment.
What this interaction means in plain words
Hydrochlorothiazide-lisinopril and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-lisinopril belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects.
What to do
Counsel the patient to avoid direct sunlight and bright light on skin and eyes for the period recommended after verteporfin infusion.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-lisinopril
- Dofetilide + Hydrochlorothiazide-lisinopril Contraindicated
- Hydrochlorothiazide-lisinopril + Sacubitril / valsartan Contraindicated
- Amifostine + Hydrochlorothiazide-lisinopril Major
- Amiloride + Hydrochlorothiazide-lisinopril Major
- Benazepril + Hydrochlorothiazide-lisinopril Major
- Bendroflumethiazide + Hydrochlorothiazide-lisinopril Major
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Hydrochlorothiazide-lisinopril with Verteporfin?
MediHelp rates the interaction as minor. Hydrochlorothiazide-lisinopril and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics are photosensitizing, and verteporfin is a photosensitizer used in photodynamic therapy. Combining them may increase the risk of skin photosensitivity reactions after treatment.
How serious is the interaction between Hydrochlorothiazide-lisinopril and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to avoid direct sunlight and bright light on skin and eyes for the period recommended after verteporfin infusion.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
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