Drug interactions
Hydroxychloroquine + Indacaterol
Severity: Moderate
Hydroxychloroquine and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxychloroquine can prolong the QT interval, and indacaterol may add to this through tachycardia and hypokalemia. This may increase the risk of torsades de pointes in susceptible patients.
What this interaction means in plain words
Hydroxychloroquine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydroxychloroquine belongs to Musculoskeletal; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-agonist-induced hypokalemia.
What to do
Check baseline ECG, potassium and magnesium in patients with cardiac risk factors, and monitor QTc during co-therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Indacaterol?
MediHelp rates the interaction as moderate. Hydroxychloroquine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydroxychloroquine can prolong the QT interval, and indacaterol may add to this through tachycardia and hypokalemia. This may increase the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Hydroxychloroquine and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG, potassium and magnesium in patients with cardiac risk factors, and monitor QTc during co-therapy.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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