Drug interactions
Hydroxychloroquine + Temsirolimus
Severity: Minor
Hydroxychloroquine and Temsirolimus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temsirolimus is immunosuppressive, while hydroxychloroquine contributes little immunosuppression, so there is no well-established additive infection risk. No clear interaction has been characterized.
What this interaction means in plain words
Hydroxychloroquine and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxychloroquine belongs to Musculoskeletal; Temsirolimus belongs to Oncology.
Why it happens
No established mechanism; only minimal theoretical additive immunomodulation.
What to do
No specific action is needed beyond standard monitoring for infection during temsirolimus therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Other interactions of Temsirolimus
- Bcg vaccine live + Temsirolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Temsirolimus Contraindicated
- Measles mumps and rubella vaccine live + Temsirolimus Contraindicated
- Measles mumps rubella and varicella vaccine live + Temsirolimus Contraindicated
- Measles vaccine + Temsirolimus Contraindicated
- Rotavirus oral vaccine live + Temsirolimus Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Temsirolimus?
MediHelp rates the interaction as minor. Hydroxychloroquine and Temsirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temsirolimus is immunosuppressive, while hydroxychloroquine contributes little immunosuppression, so there is no well-established additive infection risk. No clear interaction has been characterized.
How serious is the interaction between Hydroxychloroquine and Temsirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond standard monitoring for infection during temsirolimus therapy.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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