Drug interactions
Indacaterol + Ozanimod
Severity: Moderate
Indacaterol and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can slow heart rate and conduction, and indacaterol may prolong QTc and cause tachycardia or hypokalemia. Together they could increase the risk of arrhythmia, particularly in patients with cardiac disease.
What this interaction means in plain words
Indacaterol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Ozanimod belongs to Central Nervous System.
Why it happens
Additive effects on cardiac conduction and repolarization through pharmacodynamic mechanisms.
What to do
Obtain an ECG before starting ozanimod in patients taking indacaterol and seek cardiology advice if QT risk factors are present. Monitor heart rate, ECG and potassium during treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Indacaterol with Ozanimod?
MediHelp rates the interaction as moderate. Indacaterol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod can slow heart rate and conduction, and indacaterol may prolong QTc and cause tachycardia or hypokalemia. Together they could increase the risk of arrhythmia, particularly in patients with cardiac disease.
How serious is the interaction between Indacaterol and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG before starting ozanimod in patients taking indacaterol and seek cardiology advice if QT risk factors are present. Monitor heart rate, ECG and potassium during treatment.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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