Drug interactions
Indacaterol + Valbenazine
Severity: Moderate
Indacaterol and Valbenazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valbenazine can prolong the QT interval at higher exposures, and indacaterol may add cardiac repolarization effects. Arrhythmia risk may be raised in susceptible patients.
What this interaction means in plain words
Indacaterol and Valbenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Valbenazine belongs to Central Nervous System.
Why it happens
Additive QT prolongation and beta-agonist related hypokalemia.
What to do
Monitor ECG and electrolytes in patients with cardiac risk factors or reduced valbenazine clearance.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Valbenazine
- Deutetrabenazine + Valbenazine Contraindicated
- Tranylcypromine + Valbenazine Contraindicated
- Amiodarone + Valbenazine Major
- Amisulpride + Valbenazine Major
- Apalutamide + Valbenazine Major
- Carbamazepine + Valbenazine Major
Frequently asked questions
Can I take Indacaterol with Valbenazine?
MediHelp rates the interaction as moderate. Indacaterol and Valbenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valbenazine can prolong the QT interval at higher exposures, and indacaterol may add cardiac repolarization effects. Arrhythmia risk may be raised in susceptible patients.
How serious is the interaction between Indacaterol and Valbenazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors or reduced valbenazine clearance.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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