Drug interactions
Labetalol + Maraviroc
Severity: Moderate
Labetalol and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc has been associated with postural hypotension, particularly in patients with renal impairment or on blood pressure lowering drugs. Labetalol can add to this effect and increase the risk of dizziness and falls.
What this interaction means in plain words
Labetalol and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Labetalol belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive hypotensive effects, with alpha blockade by labetalol contributing to orthostatic changes.
What to do
Monitor orthostatic blood pressure and counsel patients about rising slowly. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Labetalol with Maraviroc?
MediHelp rates the interaction as moderate. Labetalol and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc has been associated with postural hypotension, particularly in patients with renal impairment or on blood pressure lowering drugs. Labetalol can add to this effect and increase the risk of dizziness and falls.
How serious is the interaction between Labetalol and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor orthostatic blood pressure and counsel patients about rising slowly. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What other medicines interact with Labetalol?
MediHelp also lists interactions of Labetalol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Labetalol page.
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