Drug interactions
Losartan + Maraviroc
Severity: Minor
Losartan and Maraviroc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and combining it with an antihypertensive such as losartan may increase the likelihood of dizziness or fainting. The risk is greatest in volume-depleted patients and at treatment initiation.
What this interaction means in plain words
Losartan and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Losartan belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive pharmacodynamic hypotensive effects.
What to do
Monitor blood pressure and orthostatic symptoms when maraviroc is started, and counsel patients to rise slowly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Losartan + Sparsentan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
- Amlodipine-benazepril + Losartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Losartan Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Losartan with Maraviroc?
MediHelp rates the interaction as minor. Losartan and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, and combining it with an antihypertensive such as losartan may increase the likelihood of dizziness or fainting. The risk is greatest in volume-depleted patients and at treatment initiation.
How serious is the interaction between Losartan and Maraviroc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when maraviroc is started, and counsel patients to rise slowly.
What other medicines interact with Losartan?
MediHelp also lists interactions of Losartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Losartan page.
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