Drug interactions
Mirtazapine + Triclabendazole
Severity: Moderate
Mirtazapine and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have been associated with QT prolongation, so combining them may add to the risk of arrhythmia, including torsades de pointes. The risk is greatest with electrolyte disturbances or underlying heart disease.
What this interaction means in plain words
Mirtazapine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Mirtazapine belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT interval prolongation, probably through cardiac potassium channel effects.
What to do
Check baseline ECG and correct potassium and magnesium abnormalities. Avoid the combination in patients with congenital long QT or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Mirtazapine with Triclabendazole?
MediHelp rates the interaction as moderate. Mirtazapine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have been associated with QT prolongation, so combining them may add to the risk of arrhythmia, including torsades de pointes. The risk is greatest with electrolyte disturbances or underlying heart disease.
How serious is the interaction between Mirtazapine and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and correct potassium and magnesium abnormalities. Avoid the combination in patients with congenital long QT or other QT-prolonging drugs.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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