Drug interactions
Montelukast + Tazemetostat
Severity: Minor
Montelukast and Tazemetostat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tazemetostat is a weak-to-moderate CYP3A4 inducer and may reduce montelukast exposure slightly. The clinical effect is likely small.
What this interaction means in plain words
Montelukast and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Montelukast belongs to Respiratory; Tazemetostat belongs to Miscellaneous.
Why it happens
Tazemetostat induces CYP3A4, increasing a secondary clearance pathway for montelukast.
What to do
No empirical dose change; monitor asthma or allergy control and reassess if symptoms worsen.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Montelukast
- Apalutamide + Montelukast Moderate
- Carbamazepine + Montelukast Moderate
- Deferasirox + Montelukast Moderate
- Enzalutamide + Montelukast Moderate
- Fosphenytoin + Montelukast Moderate
- Gemfibrozil + Montelukast Moderate
Other interactions of Tazemetostat
Frequently asked questions
Can I take Montelukast with Tazemetostat?
MediHelp rates the interaction as minor. Montelukast and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tazemetostat is a weak-to-moderate CYP3A4 inducer and may reduce montelukast exposure slightly. The clinical effect is likely small.
How serious is the interaction between Montelukast and Tazemetostat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change; monitor asthma or allergy control and reassess if symptoms worsen.
What other medicines interact with Montelukast?
MediHelp also lists interactions of Montelukast with, for example, Apalutamide, Carbamazepine, Deferasirox. The full list is on the Montelukast page.
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